1. 代表性科研项目 (1)国家科技部,省部级, SQ2022FY010025,我国感染相关捕食性微生物资源本底调查, 2022-10至2025-09,在研,子任务负责人 (2)成都医学院,非编码RNA实验室专项, FB19-06,基因编辑改变鲍曼不动杆菌噬菌体宿主谱的研究,2019-01至2022-12,结题,主持。 2. 代表性学术论文 （1） Xianggui Yang#, Jun Zeng#, Dan Wang#, Qin Zhou#, Xuejing Yu, Zhenguo Wang, Tingting Bai, Guangxin Luan *, Ying Xu*; NagZ modulates the virulence of E. cloacae by acting through the gene of unknown function, ECL_03795. Virulence. 2024,15(1):2367652. DOI: 10.1080/21505594.2024.2367652. （共同通讯） （2） Penggang He#, Feng Cao#, Qianyu Qu, Huaixin Geng, Xin Yang, Tong Xu, Rui Wag, Xu Jia, Mao Lu*, Peibin Zeng*, Guangxin Luan*; Host range expansion of Acinetobacter phage vB_Ab4_Hep4 driven by a spontaneous tail tubular mutation. Frontiers in Cellular and Infection Microbiology. 2024,14:1301089. DOI: 10.3389/fcimb.2024.1301089. (通讯作者) （3） Huaixin Geng#, Lingjie Song#, Xianggui Yang#, Siyu Xing, Rui Wang, Ying Xu*, Xu Jia*, Guangxin Luan*; Resistance of Klebsiella pneumoniae to Phage hvKpP3 Due to High-Molecular Weight Lipopolysaccharide Synthesis Failure, Microbiology Spectrum, 2023, 11(3). DOI: 10.1128/spectrum.04384-22. (通讯作者) （4） Qianyu Qu#, Tao Chen#, Penggang He, Huaixin Geng, Peibin Zeng*, Guangxin Luan*; Isolation and characterization of a novel lytic bacteriophage vB_Efm_LG62 infecting Enterococcus faecium, Virus Genes，2023，59(5):763-774. DOI:10.1007/s11262-023-02016-9.（通讯作者） （5） Xiaokui Zhu#, Changwu Yue#, Huaixin Geng#, Lingjie Song, Huiming Yuan, Xianqin Zhang, Chuanyu Sun, Guangxin Luan*, Xu Jia*; Coexistence of tet(A) and blaKPC-2 in the ST11 hypervirulent tigecycline- and carbapenem-resistant Klebsiella pneumoniae isolated from a blood sample, European Journal of Clinical Microbiology & Infectious Diseases, 2022, 42: 23-31. DOI: 10.1007/s10096-022-04512-6 (共同通讯) （6） Song Lingjie#, Yang Xianggui#, Huang Jinwei, Zhu Xiaokui, Han Guohui, Wan Yan, Xu Ying, Guangxin Luan *, Jia Xu*. Phage Selective Pressure Reduces Virulence of Hypervirulent Klebsiella pneumoniae Through Mutation of the wzc Gene. Frontiers in Microbiology, 2021,12:739319. DOI:10.3389/fmicb.2021.739319 (共同通讯) 3. 授权专利 (1)宋灵洁;栾广信;贾旭;一株针对高毒力肺炎克雷伯氏菌的新噬菌体及其应用, 2020-10-20,中国,CN202011128064.1 (专利) |
