1. 代表性科研项目 (1) 国家自然基金面上项目,超声介入“诱饵”脂质体级联调控血脂代谢和血管炎症以稳定斑块,82472008,2025.01-2028.12, 48万,在研,主持。 (2) 上海市卫生健康委员会卫生行业临床研究专项,应用多模态超声评估动脉弹性对斑块滋养血管的影响,202240235,2023.1.01-2025.12.31,20万,在研,主持。 (3) 上海市自然基金,PEDF抑制动脉外膜滋养血管稳定易损斑块的实验研究,21ZR1451400,2021.7.1-2024.6.30,20万,已结题,主持。 2. 代表性学术论文 (1) Luo X, Zhang M, Dai W, Xiao X, Li X, Zhu Y, Shi X, Li Z*. Targeted nanoparticles triggered by plaque microenvironment for atherosclerosis treatment through cascade effects of reactive oxygen species scavenging and anti-inflammation. J Nanobiotechnology. 2024 Jul 27;22(1):440.(IF=10.2/Q1) (2) Wang Q, Duan Y, Jing H, Wu Z, Tian Y, Gong K, Guo Q, Zhang J, Sun Y, Li Z*, Duan Y*. Inhibition of atherosclerosis progression by modular micelles. J Control Release. 2023 Feb;354:294-304.(IF=11.464/Q1) (3) Wang Q, Jing H, Lin J, Wu Z, Tian Y, Gong K, Guo Q, Yang X, Wang L, Li Z*, Duan Y*. Programmed prodrug breaking the feedback regulation of P-selectin in plaque inflammation for atherosclerotic therapy. Biomaterials. 2022 Sep;288:121705.(IF=15.304/Q1) (4) Chen J, Yang X, Li X, Jin L, Wu L, Zhang M, Du L, Luo X and Li Z*. Association between myocardial layer-specific strain and high 10-year risk of atherosclerotic cardiovascular disease in hypertension—findings from the China-PAR project study. Front. Cardiovasc. Med. 2024 October; 11:1460826.(IF=2.8/Q2) (5) Chen J, Jin L, Zhang M, Wu L, Shen C, Sun J, Du L, Luo X, Li Z*. Relation of myocardial dysfunction to biomarkers, COVID-19 severity and all-cause mortality. ESC Heart Fail. 2024 May 29. doi: 10.1002/ehf2.14881.(IF=3.8/Q2) (6) Wang Y, Chen J, Jin L, Wu L, Zhang M, Sun J, Shen C, Du L, Wang B, Li Z*. Sequence and directivity in cardiac muscle injury of COVID-19 patients: an observational study. Front Cardiovasc Med. 2023 Oct 16;10:1260971.(IF=3.9/Q2) (7) Lin Jin, Lingheng Wu, Jianxiong Chen, Mengjiao Zhang, Jiali Sun, Cuiqin Shen, Lianfang Du, Xiaoyin She, Zhaojun Li*. Uncoupling of the center-to-periphery arterial stiffness gradient and pulse pressure amplification in viral pneumonia infection. BMC Infect Dis. 2023 Oct 5;23(1):657.(IF=3.7/Q2) (8) Chen J, Jin L, Wu L, Zhang M, Wu X, Hong Y, Luo X, Li Z*. Gender and age disparities in small-to-medium arterial stiffness among the Chinese population. Nutr Metab Cardiovasc Dis. 2023 Dec;33(12):2355-2362.(IF=3.9/Q2) (9) Wu L, Zhang M, Chen J, Jin L, Shen C, Sun J, Luo X, Li Z*, Du L. A Novel Index System for Assessing Ventricular-Vascular Coupling. Rev Cardiovasc Med. 2023 Oct 8;24(10):282. (IF=4.43/Q2) (10) Jin L, Chen J, Wu L, Zhang M, Sun J, Shen C, Du L, Wang D, Li Z*. Relative contributions of arterial stiffness to cardiovascular disease risk score in Chinese women in framingham and China-PAR model. Front Cardiovasc Med. 2023 Jun 15;10:1169250.(IF=5.846/Q2) 3. 代表性专著 (1) 谢明星等,超声诊断学第5版:胎儿及新生儿分册,科技出版社;编委 (2) 罗红等,妇产经静脉超声造影图解,人民卫生出版社;编委 4. 授权专利 (1) 李朝军,罗向红,苑洁,杜联芳,刘吉斌,一种多功能鼠尾静脉注射平台;发明专利,专利号:ZL201710608111.4(发文时间2023.10.7) (2) 李朝军,罗向红,苑洁,杜联芳.一种小鼠尾静脉注射捆扎钳;发明专利,专利号:ZL201710608152.3(发文时间2023.8.16) (3) 李朝军,罗向红,苑洁,杜联芳.一种鼠尾静脉注射辅助保暖、控温、光导系统;发明专利,专利号:ZL201710606755.X(发文时间2023.5.15) (4) 李朝军,罗向红.一种超声探头扶持设备;发明专利,专利号:ZL201610674392.9.(发文时间2023.5.9) (5) 李朝军;李欣怡;罗向红;张梦娇;药物载体、胶束、抗炎和/或抗动脉粥样硬化的药物制剂、及其制备方法和应用;专利类别:发明专利,申请号:2023113066720;(申请时间2023.10.10) (6) 李朝军;李欣怡;张梦娇;罗向红;基于没食子酸-维生素E聚乙二醇琥珀酸酯的药物载体、胶束、及其制备方法和应用;专利类别:发明专利,申请号:2023113066684;(申请时间2023.10.10) 5.成果奖 (1) 李朝军(3/10); 超声造影新生血管成像提高肿瘤早期诊疗效果的关键技术建立与应用,中华医学会,中华医学科技奖二等,科技进步,其他, 2023(杜联芳;李凡;李朝军;史秋生;白敏;金利芳;蔡应娱;高峰;林丽洲;马庆庆) (2) 李朝军(3/7); 超声造影新生血管成像提高肿瘤早期诊疗效果的关键技术建立与应用,上海市医学会,上海医学科技奖二等,科技进步,其他, 2022(杜联芳;李凡;李朝军;史秋生;白敏;金利芳;蔡应娱) |