代敏
基本情况:
姓名:代敏 |
性别:女 |
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工作单位:成都医学院 |
职称:教授 |
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学位:博士 |
学历:博士研究生 |
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毕业院校:成都中医药大学 |
电子邮箱:qlzhang80@163.com |
个人简介:
教育背景:西南大学,1996.07,学士,兽医四川农业大学,2003.07,动物科技学院,硕士成都中医药大学,2010.06,药学院,博士研究方向主要研究方向为中药抗病原微生物活性及作用机制研究学术成果代表性科研项目1.四川省高校科研创新团队:细菌感染与实验室诊断四川省教育厅2.基于耐药信号通路MecR1-MecI-MecA研究草果油逆转MRSA对β-内酰胺类抗生素多重耐药的作用机制四川省科技厅3.草果油逆转MRSA对β-类酰胺类抗生素多重耐药的分子机制研究成都市科技局4.广藿香抗菌作用筛选研究成都中医药大学5.基于双组分系统KdpDE研究香叶醇调控耐甲氧西林金黄色葡萄球菌KdpFABC系统的分子机制国家自然基金委6.慢性疲劳综合征人群中医“治未病”辨识方法与干预技术示范研究国家重点研发计划中医药现代化研究重点专项7.草果油调控耐甲氧西林金黄色葡萄球菌双组份Kdp系统的分子机制研究四川省科技厅应用基础项目8.产教融合视域下医学技术学科人才培养路径探索成都市教育局代表性
学术论文
1.Long Nana, Zhang Yanjiao, Qiu Min, Deng Jingzhu, Sun Fenghui, Dai Min. Dynamic changes ofinfammatory response andoxidative stress induced bymethicillin resistant Staphylococcus aureus inmice. Eur J Clin Microbiol Infect Dis,2022;41(1):79-86.(Q3IF:3.267)2.Lin Lin, Long Nana, Qiu Min, Liu Yao, Sun Fenghui, Dai Min. The Inhibitory Efficiencies of Geraniol as an Anti-Inflammatory, Antioxidant, and Antibacterial, Natural Agent Against Methicillin-Resistant Staphylococcus aureus Infection in vivo. Infection and Drug Resistance,2021:14 2991-3000.(Q2IF:4.003)3.Cong Shen, Siyuan Feng, Hongtao Chen, Min Dai, David L Paterson, Xiaobin Zheng, Xingui Wu, Lan-Lan Zhong, Yan Liu, Yong Xia, Rui Ma, Xi Huang, Guo-Bao Tian. Transmission of mcr-1-Producing Multidrug-resistant Enterobacteriaceae in Public Transportation in Guangzhou, China. Clinical Infectious Diseases,2018, 67(suppl2): S217-S224.(Q1IF:9.055)4.Ruowen He, Yongqiang Yang, Yiping Wu, Lan-Lan Zhong, Yanxian Yang, Guanping Chen, Mingyang Qin, Xiaoxue Liang, Mohamed Abd El-Gawad El-Sayed Ahmed, Minmin Lin, Bin Yan, Yong Xia, Min Dai#, Hongtao Chen#, Guo-Bao Tian#. Characterization of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump in Klebsiella pneumoniae and Klebsiella quasipneumoniae from Patients in China. Antimicrobial Agents and Chemotherapy,2021,65(2):e02075-20.(Q1IF:5.191)5.Guo W, Ren K, Ning RH, LiCW, Zhang HM, Li DS, Xu L, Sun FH*, Dai M*. Fecal microbiota transplantation provides new insight into wildlife conservation. Global Ecology and Conservation,2020,24:e01234.(Q1IF:3.380)6.Fenghui Sun, Chaochao Yan, Yunyun Lv, Zhonghui Pu, Zedong Liao, WeiGuo*, Min Dai*.Genome Sequencing of Amomum tsao-ko Provides Novel Insight Into Its Volatile Component Biosynthesis. Frontiers in Plant Science,2022;13:904178. (Q2 IF:4.106)7.Zhong-Hui Pu, Min Dai, Liang Xiong, Cheng Peng. Total alkaloids from the rhizomesof Ligusticum striatum: a review of chemical analysis and pharmacological activities. NATURAL PRODUCT RESEARCH,2020,9:1-18.(Q2IF:2.862)8.Long Nana,Tang Huaqiao, Lin Lin, Li Jianlong, Guo Lijuan, Sun Fenghui, Dai Min.Effects of infection of MRSA on the expression and activity of renal cytochrome P450s in mice. The Journal of Toxicological Sciences,2019,44(4):299-307.(Q4IF:1.737)9. Long Nana, Tang Huaqiao, Sun Fenghui, Lin Lin, Dai Min. Effect and mechanismof citral against methicillin-resistant Staphylococcus aureus in vivo. Journal of the Science of Food and Agriculture,2019,99(9):4423-4429. (Q1IF:2.614)10.Huaqiao Tang, Nana Long, Lin Lin, Yao Liu, Jianlong Li, Fenghui Sun, Lijuan Guo, Fen Zhang, Min Dai. Effect of MRSA on cYP450: dynamic changes ofcytokines,oxidative stress, and drug-metabolizing enzymes in mice infected with MRSA. Infection and DrugResistance,2018,(11):229-238.(Q2IF:3.000)11.Huaqiao Tang, Nana Long, Min Dai*, Lin Lin, Jianlong Li, Fenghui Sun, Lijuan Guo. Effect of citral onmouse hepatic cytochrome P450 enzymes. Pharmaceutical Biology,2018,56(1):337-343. (Q2IF:2.492)12.Min Dai, Cheng Peng, Fenghui Sun. Anti-infectious efficacy of essential oil from Caoguo (Fructus Tsaoko). Journal of Traditional Chinese Medicine,2016,36(6):799-804. (Q4IF:0.991)13.Min Dai, Cheng Peng, Fu Peng, Chengbin Xie, Pinjia Wang, Fenghui Sun. Anti-Trichomonas vaginalis properties of the oil of Amomum tsao-ko and its major component,geraniol. Pharm Biol,2016,54(3):445-450.(Q3IF: 1.916)14.Long N, Deng J, Qiu M, Zhang Y, Wang Y, Guo W, Dai M*, Lin L*. Inflammatory and pathological changes in Escherichia coli infected mice. Heliyon. 2022,Dec 24: e12533.15. Wei Guo, Min Qiu, Zhonghui Pu, Nana Long, Min Yang, Ke Ren, Ruihong Ning,Siyuan Zhang, Fu Peng*, Fenghui Sun*, Min Dai*. Geraniol-a potential alternative to antibiotics for bovine mastitis treatment without disturbing the host microbial community or causing drug residues and resistance. Front Cell Infect Microbiol, 2023;13:1126409. 16. Xiaoxue Liang, Ping Chen, Baoguo Deng, Feng-Hui Sun, Yongqiang Yang, Yanxian Yang, Ruowen He, Mingyang Qin, Yiping Wu, Fan Yang, Guo-Bao Tian, Min Dai.Outcomes and Risk Factors of Bloodstream Infections Caused by Carbapenem-Resistantand Non-Carbapenem-Resistant Klebsiella pneumoniae in China. Infection and Drug Resistance,2022,15:3161-3171. (Q2 IF:3.000)
授权专利
1.香叶醇在制备治疗阴道炎的药物中的用途,ZL201210216091.3,第二完成人2.草果在制备治疗和/或预防大肠杆菌的中兽药中的用途,ZL201410828727.9,第二完成人3.柠檬醛及衍生物在制备MRSA感染性疾病药物中的新用途,ZL201810204915.2,第一完成人4.一种赖氨酸芽孢杆菌及其在降解农药中的应用,ZL201611000659.2,第二完成人5.香叶醇及其衍生物在制备MRSA感染性疾病药物中的新用途,ZL201810204934.5,第一完成人6.草果油的新用途,ZL201710344984.9,第一完成人7.一种淀粉芽孢杆菌及其在降解氨基甲酸酯类农药中的应用,ZL201611000660.5,第二完成人8.草果油在制备治疗阴道炎的药物中的用途,ZL201210215589.8,第二完成人9.一种手动压力过滤装置,ZL201620605511.0,第二完成人10.一种可紧缩的压力装置,ZL201720399254.4,第二完成人
其他:
教学工作:本科教学:《微生物学检验》 研究生教学:《感染与耐药》国家一流专业医学检验技术专业负责人
荣誉奖励成果奖励:1.四川省科技进步二等奖中药防控细菌耐药性的关键技术与应用2021年排名第一2.临床医药研究突出成就奖2021年中国药学发展奖排名第一3.中华医学科技三等奖中药防控多重耐药病原菌传播与感染关键技术创新与应用2022年排名第一
荣誉:1.四川省“青城计划”天府万人科技领军人才2.四川省第十三批有突出贡献的优秀专家3.四川省卫生健康领军人才4.四川省中医药管理局学术和技术带头人5.四川省卫生健康领军人才和学术技术带头人6.四川省第十批学术和技术带头人后备人选7.四川省高校创新团队“细菌感染与实验室诊断”带头人
社会兼职:1.四川省普通本科高等学校医学技术类专业教学指导委员会副主任委员2.世界中医药学会联合会道地药材多维评价专业委员会理事3.四川省技术创新促进会食品营养与安全专家委员会副主任委员