姓名：赵威

性别：男

1. 代表性科研项目

（1） 国家自然科学基金青年科学基金项目，探究ASAP1-IT1在非小细胞肺癌细胞顺铂耐药机制中的作用，主持

（2） 南京市医学科技发展重点项目，探究非小细胞肺癌病人血液中去甲肾上腺素水平与肿瘤发生及转移的关系，主持

（3） 江苏省博士后科研资助计划，利用原代非小细胞肺癌细胞3D培养平台优化常规化疗方案，主持

（4） 四川省科技厅面上项目，E3泛素连接酶WWP1促进非酒精性脂肪肝进展及治疗中作用研究，主持

2. 代表性学术论文

（1） Zhuang, L., Li, Q., You, W., Wen, S., Chen, T., Su, J., Zhao, W., and Hu, J. (2024) Complement C3 promotes islet β-cell dedifferentiation by activating Wnt/β-catenin pathway. iScience 27, 111064，共同通讯

（2） Zhuang, J. L., Zhang, L. L., Zhang, S. Y., Zhang, Z. Q., Xie, T. L., Zhao, W., and Liu, Y. T. (2024) Membrane-associated RING-CH 7 inhibits stem-like capacities of bladder cancer cells by interacting with nucleotide-binding oligomerization domain containing 1. Cell Biosci 14，通讯

（3） Xie, T., Peng, S., Liu, S., Zheng, M., Diao, W., Ding, M., Fu, Y., Guo, H., Zhao, W., and Zhuang, J. (2024) Multi-cohort validation of Ascore: an anoikis-based prognostic signature for predicting disease progression and immunotherapy response in bladder cancer. Molecular Cancer 23，共同通讯

（4） Zhao, T., Sun, J., Lu, X., Liu, L., Chen, L., Zhao, W., and Zhou, B. (2023) Let‐7a‐5p abrogates progression of papillary thyroid carcinoma cells by decreasing nuclear receptor subfamily 6 group a member 1‐mediated lipogenesis. Journal of Biochemical and Molecular Toxicology，共同通讯

（5） Li, H. T., Zhong, K., Xia, Y. F., Song, J., Chen, X. Q., Zhao, W., Zeng, X. H., and Chen, T. X. (2023) Puerarin improves busulfan-induced disruption of spermatogenesis by inhibiting MAPK pathways. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 165, 115231，共同通讯

（6） Chen, T., Meng, Y., Zhou, Z., Li, H., Wan, L., Kang, A., Guo, W., Ren, K., Song, X., Chen, Y., and Zhao, W. (2023) GAS5 protects against nonalcoholic fatty liver disease via miR-28a-5p/MARCH7/NLRP3 axis-mediated pyroptosis. Cell death and differentiation，通讯

（7） Zhang, Z., Xie, T., Zhang, S., Yin, H., Zhang, X., Zhang, S., Chen, W., Yu, D., Qiu, X., Zhao, W., Guo, H., and Zhuang, J. (2023) Second generation androgen receptor antagonist, TQB3720 abrogates prostate cancer growth via AR/GPX4 axis activated ferroptosis. Frontiers in pharmacology 14, 1110146，共同通讯

（8） Yang, Y., Huang, R., Xiang, L., Zeng, J., Zhao, W., and Huang, N. (2023) Invasive mucinous adenocarcinoma misdiagnosed as pneumonia: A case report. Experimental and therapeutic medicine 25, 168，共同通讯

（9） Zhou, Y., Yang, D., Qiang, Z., Meng, Y., Li, R., Fan, X., Zhao, W., and Meng, Y. (2022) Ribosome-inactivating protein MAP30 isolated from Momordica charantia L. induces apoptosis in hepatocellular carcinoma cells. Recent patents on anti-cancer drug discovery，共同通讯

（10） Sun, Q., Gui, Z., Zhao, Z., Xu, W., Zhu, J., Gao, C., Zhao, W., and Hu, H. (2022) Overexpression of LncRNA MNX1-AS1/PPFIA4 Activates AKT/HIF-1α Signal Pathway to Promote Stemness of Colorectal Adenocarcinoma Cells. Journal of Oncology 2022, 1-16，共同通讯

（11） Yao, B., Zhang, Q., Yang, Z., An, F., Nie, H., Wang, H., Yang, C., Sun, J., Chen, K., Zhou, J., Bai, B., Gu, S., Zhao, W., and Zhan, Q. (2022) CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m(6)A-modified CREB1 mRNA. Molecular cancer 21, 140，共同通讯

（12） Zhou, J., Wang, Y., Zhang, L., Chen, Q., Zhu, X., Jiang, P., Jiang, N., Zhao, W., and Li, B. (2022) Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1. Frontiers in pharmacology 13，共同通讯